Apoptosis: molecular regulation of cell death.

The field of apoptosis is unusual in several respects. Firstly, its general importance has been widely recognised only in the past few years and its surpri...

AJ Hale，CA Smith，LC Sutherland，... - 《European Journal of Biochemistry》

Apoptosis: molecular regulation of cell death

The field of apoptosis is unusual in several respects. Firstly, its general importance has been widely recognised only in the past few years and its surpri...

AJ Hale，CA Smith，LC Sutherland，... - Springer, Berlin, Heidelberg

Immunohistochemical analysis of bcl-2, bax, bcl-X, and mcl-1 expression in prostate cancers.

Proteins encoded by bcl-2 family genes are important regulators of programmed cell death and apoptosis. Alterations in the expression of these apoptosis-re...

M Krajewska - 《American Journal of Pathology》

Erratum: Molecular regulation of cell death (Eur. J. Biochem. 236, No. 1 (6))

To determine whether the toxic effects and changes in many cell functions caused by antitumor 1-nitroacridines are related to their enzymatically mediated covalent interstrand DNA cross-linking (J. Konopa, J. W. Pawlak, and K. Pawlak. Ch...

AJ Hale，CA Smith，LC Sutherland，... - 《European Journal of Biochemistry》

Elevated Expression of Bcl-X and Reduced Bak in Primary Colorectal Adenocarcinomas

Expression of several members of the BCL-2 family of genes was investigated by immunohistochemical methods in 30 primary colorectal adenocarcinomas and 24 ...

M Krajewska，SF Moss，S Krajewski，... - 《Cancer Research》

Reduced Expression of Proapoptotic Gene BAX Is Associated with Poor Response Rates to Combination Chemotherapy and Shorter Survival in Women with Metastati...

Bax is a homologue of Bcl-2 that promotes apoptosis. Bax protein levels were assessed by immunohistochemical methods in primary tumors derived from 119 wom...

S Krajewski，C Blomqvist，K Franssila，... - 《Cancer Research》

Cell death by apoptosis: Basic concepts and disease relevance for the gastroenterologist

Elsevier's Scopus, the largest abstract and citation database of peer-reviewed literature. Search and access research from the science, technology, medicine, social sciences and arts and humanities fields.

FG Que，GJ Gores - 《Gastroenterology》

The role of apoptosis in the pathogenesis and treatment of diseases

In adult multicellular organisms, homeostasis is determined in each cell lineage by a balance between cell death and cell growth. Dysregulation of cell dea...

E Solary，L Dubrez，B Eymin - 《European Respiratory Journal》

Hypersensitivity of Human Testicular Tumors to Etoposide-induced Apoptosis Is Associated with Functional p53 and a High Bax:Bcl-2 Ratio

Metastatic testicular cancers are curable, whereas bladder cancers and most other solid tumors are not. Cell lines derived from human testicular (GH, GCT27...

CM Chresta，JRW Masters，JA Hickman - 《Cancer Research》