Regulation of cell death: the calcium–apoptosis link
摘要：
To live or to die? This crucial question eloquently reflects the dual role of Ca<sup>2+</sup> in living organisms – survival factor or ruthless killer. It has long been known that Ca<sup>2+</sup> signals govern a host of vital cell functions and so are necessary for cell survival. However, more recently it has become clear that cellular Ca<sup>2+</sup> overload, or perturbation of intracellular Ca<sup>2+</sup> compartmentalization, can cause cytotoxicity and trigger either apoptotic or necrotic cell death.
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DOI：
10.1038/nrm1150
年份：
2003
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