Cross-talk between the insulin and angiotensin signaling systems.

阅读量:

62

作者:

LA VellosoF FolliXJ SunMF WhiteMJ SaadCR Kahn

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摘要:

The miniaturization of devices and the advances in nanotechnology-enabled products has led to the requirement of an increased understanding of the various interactions present in nano-scale contacts - including adhesion and surface tension. It is well known that adhesion plays an important role in the tribological behavior and contact mechanics of many modern nemo-devices and will affect future products currently under development. Adhesion of materials is ruled by interactions that extend down to the atomic scale of the contributing materials. The forces involved include non-covalent interactions such as Van-der-Waals forces, hydrogen bonds and Coulomb forces as well as covalent chemical bonds. Although Van-der-Waals forces are only short range, they often rule the adhesion between two materials and are therefore responsible for contact interaction between two films. While the adhesion between two materials is one important factor, the elasticity of both is also very important. This elasticity has a major influence on the size of a contact area that is developed underneath a point contact when a certain force is active. Modern instruments for nanoindentation are sensitive enough to detect the small surface forces and to study adhesion effects.

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DOI:

10.1073/pnas.93.22.12490

被引量:

1303

年份:

1996

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2006
被引量:93

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