PDE11A mutations in adrenal disease

The invention provides previously uncharacterized variants of PDE11A that are correlated with a newly discovered form of Cushing Syndrome that presents at a young age. The invention also provides methods useful to research, screen for, t...

CA Stratakis - WO

Microparticles useful as ultrasonic contrast agents

not available for EP1202671

TB Ottoboni，RE Short，RK Yamamoto - US

Modified carrier particles for use in dry powder inhalers

The invention relates to carrier particles for use in pharmaceutical compositions for the pulmonary administration of medicaments by means of dry powder inhalers. In particular, the invention relates to a novel technological process for ...

R Musa，R Bilzi，P Ventura，...

Medical implants and anti-scarring agents

Implants are used in combination with an anti-scarring agent in order to inhibit scarring that may otherwise occur when the implant is placed within an animal. The agent may be any suitable anti-scarring agent, e.g., a cell cycle inhibit...

WL Hunter，DM Gravett，PM Toleikis，...

Human interferon-&egr : a type I interferon

The invention concerns a novel human interferon-ε, originally designated PRO655, and its variants and derivatives. The novel interferon is related to but distinct from members of the IFN-α family and from IFNs-β and -γ. Nucleic acid ...

J Chen，P Godowski，Wood, William I.，...

MOISTURIZING AND LUBRICATING COMPOSITIONS

The present invention is generally directed to moisturizing and lubricating compositions for use on the bodyfacing surface of an absorbent product or on one or both faces of a tissue product. The moisturizing and lubricating compositions...

WR Joseph，K Clarke，DG Krzysik，...

Nicotine and Chocolate Compositions

The present invention is drawn to nicotine-containing pharmaceutical compositions that comprise chocolate and method of using the compositions in different therapies, such as nicotine replacement therapy.

T Landh，NO Lindberg - US

Clostridial toxin derivatives and methods for treating pain

Agents for treating pain, methods for producing the agents and methods for treating pain by administration to a patient of a therapeutically effective amount of the agent. The agent can include a clostridial neurotoxin, or a component or...

S Donovan - US

Clostridial toxin pharmaceutical compositions

A botulinum toxin pharmaceutical formulation free of animal derived proteins, comprising a botulinum toxin and a recombinant albumin, suitable for therapeu...

TJ Hunt

Antibiotics AW998A, AW998B, AW998C and AW998D

This invention relates to antibiotics selected from the group AW998A, AW998B, AW998C and AW998D derived from the microorganism Streptomyces designated LL-A...

F Kong，GT Carter，SW Luckman