Carcinogenic action of quinoxaline 1,4-dioxide in rats.
摘要：
Quinoxaline 1,4-dioxide was fed to 400 rats at levels of 10 mg or 1 mg/kg body weight for 18 months. It produced a high incidence of nasal and liver tumors only in the group fed 10 mg/kg. Of diverse histologies, the nasal tumors included anaplastic carcinomas, adenocarcinomas, squamous cell carcinomas, neuroepitheliomas, basal cell carcinomas, and a single fibrosarcoma. The nasal epithelium not involved in the neoplastic process showed dysplasia and hyperplasia.
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DOI：
10.1093/jnci/55.1.137
被引量：
年份：
1975
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来源期刊
Journal of the National Cancer Institute
1975 Jul;
引用走势
2008
被引量：7
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