Fibrogenic cytokines and connective tissue production.
摘要：
The pathogenesis of fibrotic disorders is similar regardless of the tissues involved. Inflammatory leukocytes infiltrate the site triggered by chemotactic and activating mediators. This is followed by the elaboration of cytokines that directly and indirectly induce the proliferation of fibroblasts and endothelial cells and the deposition of extracellular matrix (ECM). In the absence of inhibitory signals, the continued production of these mediators sustains the connective tissue accumulation, which results in permanent alteration in tissue structure and function.
展开
关键词：
Animals Humans Connective Tissue Fibroblasts Macrophages Extracellular Matrix Pulmonary Fibrosis Fibrosis Inflammation Amino Acid Sequence
DOI：
10.1006/excr.1994.1225
被引量：
年份：
1994
BMJ
Wiley
Semantic Scholar
Oxford Univ Press
NCBI
查看更多
NCBI
Europe PMC
ResearchGate
ResearchGate
(全网免费下载)
EBSCO
onAcademic
jleukbio.org
SAGE
mcponline.org
mysciencework.com
fasebj.org
hyper.ahajournals.org
fasebj.org
(全网免费下载)
jasn.asnjournals.org
jimmunol.org
cghjournal.org
uic.pure.elsevier.com
deepdyve.com
mendeley.com
www.socolar.com
jpet.aspetjournals.org
ResearchGate
(全网免费下载)
fasebj.org
(全网免费下载)
通过文献互助平台发起求助，成功后即可免费获取论文全文。
相似文献
参考文献
引证文献
来源期刊
引用走势
辅助模式
引用
文献可以批量引用啦~
欢迎点我试用！
