Multifunctional strands in tight junctions.
摘要：
Tight junctions are one mode of cell-cell adhesion in epithelial and endothelial cellular sheets. They act as a primary barrier to the diffusion of solutes through the intercellular space, create a boundary between the apical and the basolateral plasma membrane domains, and recruit various cytoskeletal as well as signalling molecules at their cytoplasmic surface. New insights into the molecular architecture of tight junctions allow us to now discuss the structure and functions of this unique cell-cell adhesion apparatus in molecular terms.
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关键词：
Animals Humans Membrane Lipids Membrane Proteins Protein Structure, Tertiary Cell Adhesion Tight Junctions Permeability Models, Biological
DOI：
10.1038/35067088
被引量：
年份：
2001
Nature
Nature
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掌桥科研
万方医学
Ingenta
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