Pulmonary crystal-storing histiocytosis diagnosed by computed tomography-guided fine-needle aspiration

阅读量：

作者：

Todd，William，U.，Drabick，Joseph，J.，Benninghoff，Michael，G.，Frauenhoffer

展开

摘要：

Crystal-storing histiocytosis (CSH) is a rare process most often occurring in conjunction with an underlying hematopoietic neoplasm, usually multiple myeloma or low-grade B-cell lymphoma. We report the first case of pulmonary CSH diagnosed by fine-needle aspiration biopsy. A patient with a history of urothelial carcinoma developed a lung nodule, which was evaluated by fine-needle aspiration biopsy. Cytologic examination revealed macrophages with abundant cytoplasmic crystals diagnostic of CSH. Based on this cytologic interpretation, additional clinical laboratory evaluation was pursued and revealed a previously unknown monoclonal serum protein. CSH must be differentiated from other non-neoplastic and neoplastic lesions and when diagnosed, should trigger a search for an underlying lymphoproliferative disorder. Diagn. Cytopathol. 2010. 2009 Wiley-Liss, Inc.

展开

关键词：

Humans Lung Histiocytosis, Langerhans-Cell Radiography, Thoracic Positron-Emission Tomography Tomography, X-Ray Computed Biopsy, Fine-Needle Aged Crystallization Female