Fluorogenic phospholipid substrate to detect lysophospholipase D/autotaxin activity.
摘要：
[reaction: see text] D (), also known as (), is an important source of the potent mitogen (). Two fluorogenic substrate analogues for were synthesized in nine steps from (S)-PMB-. The substrates (FS-2 and FS-3) show significant increases in fluorescence when treated with recombinant and have potential applications in screening for this emerging drug target.
展开
关键词：
Multienzyme Complexes Pyrophosphatases Phosphoric Diester Hydrolases Phosphodiesterase I Phospholipids Lysophospholipids Fluorescent Dyes Molecular Structure
DOI：
10.1021/ol060414i
被引量：
年份：
2006
通过文献互助平台发起求助，成功后即可免费获取论文全文。
相似文献
参考文献
引证文献
来源期刊
引用走势
站内活动
辅助模式
引用
文献可以批量引用啦~
欢迎点我试用！
