Identification and characterization of a self-regulated repressor of translocation of the Tn3 element.
摘要:
Gene fusions that bring expression of the lacZ gene under control of transcriptional and translational signals within the transposable element Tn3 have been used to study regulation of Tn3-specified proteins. A gene encoding a 21,355-Mrpeptide that represses translocation of Tn3 and acts at the level of transcription to regulate its own synthesis has been identified and sequenced; amber, missense, and cis-dominant (operator-constitutive) point mutations in this gene have been isolated and characterized.
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DOI:
10.1073/pnas.76.8.4020
被引量:
年份:
1979
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