Renal toxicity in man treated with mitomycin C
摘要:
Thirty-two patients with metastatic carcinomas were treated with mitomycin C. Three of them developed renal toxicity within 6 to 7 months of therapy. The toxic effect was mainly on the glomerular tuft and especially on the nuclei. Nephrotoxicity of mitomycin C has been noticed in rhesus monkeys, but has never been reported in man. Patients who are being treated with mitomycin C should be observed for a rising blood urea nitrogen, serum creatinine, and albuminuria.
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DOI:
10.1002/1097-0142(1971)28:5<1314::AID-CNCR2820280534>3.0.C
被引量:
年份:
1971
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