Incorporating chemical modification constraints into a dynamic programming algorithm for prediction of RNA secondary structure

A dynamic programming algorithm for prediction of RNA secondary structure has been revised to accommodate folding constraints determined by chemical modifi...

DH Mathews，MD Disney，JL Childs，... - 《Proceedings of the National Academy of Sciences of the United States of America》

Telomere length regulation.

Telomeres are the components of chromosome ends that provide stability and allow the complete replication of the ends. Telomere length is maintained by a b...

Greider，C W - 《Annual Review of Biochemistry》

A Mammalian Telomerase-Associated Protein

The telomerase ribonucleoprotein catalyzes the addition of new telomeres onto chromosome ends. A gene encoding a mammalian telomerase homolog called TP1 (t...

Harrington，L. - 《Science》

A mammalian telomerase

The telomerase ribonucleoprotein catalyzes the addition of new telomeres onto chromosome ends. A gene encoding a mammalian telomerase homolog called TP1 (t...

L Harrington，T Mcphail，V Mar，... - 《Science》

Telomerase in the human organism.

The intent of this review is to describe what is known and unknown about telomerase in somatic cells of the human organism. First, we consider the telomera...

K Collins，JR Mitchell - 《Oncogene》

The telomerase reverse transcriptase: components andregulation

Genes Dev. 1998 Apr 15;12(8):1073-85. Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S.; Review

CI Nugent，V Lundblad - 《Genes & Development》

A role for a novel 'trans-pseudoknot' RNA–RNA interaction in the functional dimerization of human telomerase

The integral RNA (hTER) of the human telomerase ribonucleoprotein has a conserved secondary structure that contains a potential pseudoknot. Here we examine...

Ly，H. - 《Genes & Development》

Using an RNA secondary structure partition function to determine confidence in base pairs predicted by free energy minimization

The integral RNA (hTER) of the human telomerase ribonucleoprotein has a conserved secondary structure that contains a potential pseudoknot. Here we examine...

Mathews，D.，H. - RNA -CAMBRIDGE-

Telomerase RNA bound by protein motifs specific to telomerase reverse transcriptase.

Telomerase reverse transcriptase (TERT) differs from many other reverse transcriptases in that it remains stably associated with its template-containing RN...

TM Bryan，KJ Goodrich，TR Cech - 《Molecular Cell》

Ciliate telomerase biochemistry.

Telomerase is a cellular reverse transcriptase specialized for use of a template carried within the RNA component of the enzyme ribonucleoprotein complex. ...

K Collins - 《Annual Review of Biochemistry》