THE ULTRASTRUCTURAL BASIS OF CAPILLARY PERMEABILITY STUDIED WITH PEROXIDASE AS A TRACER
摘要：
The transendothelial passage of horseradish peroxidase, injected intravenously into mice, was studied at the ultrastructural level in capillaries of cardiac and skeletal muscle. Peroxidase appeared to permeate endothelial intercellular clefts and cell junctions. Abnormal peroxidase-induced vascular leakage was excluded. Neutral lanthanum tracer gave similar results. The endothelial cell junctions were considered to be maculae occludentes, with gaps of about 40 A in width between the maculae, rather than zonulae occludentes. Some observations in favor of concurrent vesicular transport of peroxidase were also made. It is concluded that the endothelial cell junctions are most likely to be the morphological equivalent of the small pore system proposed by physiologists for the passage of small, lipid-insoluble molecules across the endothelium.
展开
DOI：
10.1083/jcb.35.1.213
被引量：
年份：
1967
Taylor & Francis
Wiley
Semantic Scholar
(全网免费下载)
Semantic Scholar
掌桥科研
查看更多
NCBI
NCBI
Europe PMC
(全网免费下载)
NCBI
(全网免费下载)
Europe PMC
JBC
ResearchGate
ProQuest
EBSCO
Citeseer
Citeseer
(全网免费下载)
jacionline.org
onAcademic
ajplung.physiology.org
SAGE
deepdyve.com
circres.ahajournals.org
rupress.org
joe.endocrinology-journals.org
jcs.biologists.org
core.kmi.open.ac.uk
perspectivesinmedicine.cshlp.org
mysciencework.com
core.ac.uk
jcb.rupress.org
(全网免费下载)
www.socolar.com
jcb.rupress.org
mendeley.com
biomedsearch.com
(全网免费下载)
Semantic Scholar
(全网免费下载)
NCBI
(全网免费下载)
Europe PMC
(全网免费下载)
Citeseer
(全网免费下载)
jcb.rupress.org
(全网免费下载)
biomedsearch.com
(全网免费下载)
通过文献互助平台发起求助，成功后即可免费获取论文全文。
相似文献
参考文献
引证文献
辅助模式
引用
文献可以批量引用啦~
欢迎点我试用！
