Neural Mechanisms of a Genome-Wide Supported Psychosis Variant

Schizophrenia is a devastating, highly heritable brain disorder of unknown etiology. Recently, the first common genetic variant associated on a genome-wide...

 - 《Science》

Bi-directional effects of GABAB receptor agonists on the mesolimbic dopamine system

Nature Neuroscience offers a unique mix of opinion and reviews alongside top-quality research papers. Published monthly, in print and online, the journal r...

HG Cruz，T Ivanova，ML Lunn，... - 《Nature Neuroscience》

High-affinity binding site for ??-hydroxybutyrate in rat brain

The existence of a specific synthesizing enzyme for γ-hydroxybutyric acid in rat brain has recently been reported. Here, for the first time, we demonstrat...

J Benavides，JF Rumigny，JJ Bourguignon，... - 《Adv Biochem Psychopharmacol》

Neural mechanisms of a genome-wide supported psychosis variant.

Schizophrenia is a devastating, highly heritable brain disorder of unknown etiology. Recently, the first common genetic variant associated on a genome-wide...

 - 《Science》

The role of the nucleus accumbens and rostral anterior cingulate cortex in anhedonia: Integration of resting EEG, fMRI, and volumetric techniques

Anhedonia, the reduced propensity to experience pleasure, is a promising endophenotype and vulnerability factor for several psychiatric disorders, includin...

J Wacker，DG Dillon，DA Pizzagalli - 《Neuroimage》

Extracellular events induced by gamma-hydroxybutyrate in striatum: a microdialysis study.

The modification of dopamine release and accumulation induced by gamma-hydroxybutyrate (GHB) was studied using both striatal slices and in vivo microdialys...

V Hechler，S Gobaille，JJ Bourguignon，... - 《Journal of Neurochemistry》

Distinguishing specific sexual and general emotional effects in fMRI-subcortical and cortical arousal during erotic picture viewing.

Sexual activity involves excitement with high arousal and pleasure as typical features of emotions. Brain activations specifically related to erotic feelin...

M Walter，F Bermpohl，H Mouras，... - 《Neuroimage》

Stimulant-induced enhanced sexual desire as a potential contributing factor in HIV transmission.

OBJECTIVE: Stimulant abuse is associated with an increased risk of contracting human immunodeficiency virus (HIV). Although sharing of contaminated needles...

ND Volkow，GJ Wang，JS Fowler，... - 《Am J Psychiatry》

gamma-Hydroxybutyric acid (GHBA) induces pacemaker activity and inhibition of substantia nigra dopamine neurons by activating GABAB-receptors

In the present study the actions of 纬-hydroxybutyric acid (GHBA) on dopaminergic neurons in the rat substantia nigra (SN) were pharmacologically analysed ...

G Engberg，H Nissbrandt - Naunyn-Schmiedeberg's archives of pharmacology

Functional neuroimaging studies of sexual arousal and orgasm in healthy men and women: A review and meta-analysis

In the present study the actions of 纬-hydroxybutyric acid (GHBA) on dopaminergic neurons in the rat substantia nigra (SN) were pharmacologically analysed ...

Stoleru，S.，Fonteille，... - 《Neuroscience & Biobehavioral Reviews》