WHO Classification of Tumours of Haematopoietic and Lymphoid Tissueis the third volume in the new WHO series on histological and genetic typing of human tu...
The World Health Organization (WHO) classification has been developed under the joint auspices of the European Association for Hematopathology (EAHP) and t...
Non-Hodgkin lymphoma (NHL) is a collective term for a heterogeneous group of lymphoproliferative malignancies with differing patterns of behavior and responses to treatment.NHL must be distinguished from Hodgkin disease with certainty be...
Non-Hodgkin lymphoma (NHL) is a collective term for a heterogeneous group of lymphoproliferative malignancies with differing patterns of behavior and responses to treatment.NHL must be distinguished from Hodgkin disease with certainty be...
Harris NL,Jaffe ES,Diebold J,et al.The World Health Organization classification of neoplasms of the hematopoietic and lymphoid tissues: report of the ...
The new World Health Organization (WHO) classification of hematopoietic and lymphoid malignancy represents the first worldwide consensus document on the cl...
The new World Health Organization (WHO) classification of hematopoietic and lymphoid malignancy represents the first worldwide consensus document on the cl...
The NPM-ALK fusion gene, formed by the t(2;5)(p23;q35) translocation in non-Hodgkin's lymphoma, encodes a 75-kDa hybrid protein that contains the amino-ter...
UPDATED KIEL CLASSIFICATION FOR LYMPHOMAS. By - A.G. Stansfeld, J. Diebold, Y. Kapanci, G. Kelényi, K. Lennert, O. Mioduszewska, H. Noel, F. Rilke, C. Sun...
Acquired chromosomal anomalies (most commonly translocations) in lymphoma and leukemia usually result in either activation of a quiescent gene (by means of...
MDX-060 is a human anti-CD30 immunoglobulin (Ig) G1kappa monoclonal antibody that inhibits growth of CD30-expressing tumor cells in preclinical models. To ...
Anaplastic lymphoma kinase (ALK) is a receptor tyrosine kinase, the normal role of which remains to be completely elucidated. Although work carried out in ...
The increasing need of collecting high quality blood components and of improving the overall productivity of a blood centre requires the utilisation of a n...
Tyrosine kinases are involved in the pathogenesis of most cancers. However, few tyrosine kinases have been shown to have a well-defined pathogenetic role i...
The anaplastic lymphoma kinase (ALK) gene is characteristically translocated in Anaplastic Large Cell Lymphomas (ALCL) and the juxtaposition of the ALK gen...
More than half of anaplastic large-cell lymphomas (ALCLs) have a chromosomal translocation t(2;5) that leads to the expression of a hybrid protein composed...
PURPOSE: Rearrangement of MYC occurs in a proportion of diffuse large B-cell lymphomas (DLBCL), where they may be associated with an adverse clinical outco...
Chronic lymphocytic leukemia (CLL) is the most common leukemia among adults in Western countries. Chromosomal abnormalities commonly found using convention...
Peripheral T-Cell lymphomas (PTCL) are relatively rare diseases but appear to be highly aggressive and display worse remission and survival rates than B-ce...
The 2008 WHO Classification of Tumors of Haematopoietic and Lymphoid Tissues has introduced two new categories of high-grade B-cell lymphomas: entities in ...
Although multiparameter flow cytometry (MFC) has demonstrated clinical relevance in monoclonal gammopathy of undetermined significance (MGUS)/myeloma, immu...
In the novel WHO classification 2008, the classification of aggressive B-cell lymphoma has been revised for several categories with the aim to define "clea...
The human germinal center-associated lymphoma (HGAL) gene has prognostic value in diffuse large B-cell lymphoma, and expression of its cognate protein is g...
An aberrant immunophenotype and monoclonality of intraepithelial lymphocytes (IELs) are frequently found in refractory coeliac disease (RCD). However, the ...
