Direct Catalytic Asymmetric Aldol Reactions of Aldehydes with Unmodified Ketones

Up to 94%ee can be achieved in the title reaction [Eq. (a)], which was previously only possible with enzymes. In this reaction LaLi3 tris(binaphthoxide) (L...

YMA Yamada，N Yoshikawa，H Sasai，... - 《Angewandte Chemie International Edition in English》

Direct Catalytic Asymmetric Aldol Reactions of Aldehydes with Unmodified Ketones

Up to 94% ee can be achieved in the title reaction [Eq. (a)], which was previously only possible with enzymes. In this reaction LaLi3tris(binaphthoxide) (L...

YMA Yamada，N Yoshikawa，H Sasai，... - 《Cheminform》

Lanthanide Complexes in Multifunctional Asymmetric Catalysis

Lanthanide-based multifunctional complexes constitute a significant part of enantioselective catalysis. Thus, lanthanides are characterized by their abilit...

M Shibasaki，N Yoshikawa - 《Chemical Reviews》

Enantioselective Michael reaction of malonates to nitroolefins catalyzed by bifunctional organocatalysts.

Michael reaction of malonates to nitroolefins with chiral bifunctional organocatalysts, bearing both a thiourea and tertiary amino group, afforded Michael ...

T Okino，Y Hoashi，Y Takemoto - 《Cheminform》

Activation of carbonyl compounds by double hydrogen bonding: an emerging tool in asymmetric catalysis.

Forsee ChemInformin Full Text.

PM Pihko - 《Angewandte Chemie》

Asymmetric Organocatalysis

The field of asymmetric organocatalysis is rapidly developing and attracts an increasing number of research groups around the world. Here we present a brie...

Seayad, J，B List - 《Organic & Biomolecular Chemistry》

Asymmetric Aminocatalysis

This account focuses on novel amine-catalyzed reactions recently discovered in our laboratories. Among the newly developed transformations are efficient pr...

B List - 《Synlett》

Amino Acid Catalyzed Direct Asymmetric Aldol Reactions:  A Bioorganic Approach to Catalytic Asymmetric Carbon−Carbon Bond-Forming Reactions

Direct asymmetric catalytic aldol reactions have been successfully performed using aldehydes and unmodified ketones together with commercially available chiral cyclic secondary amines as catalysts. Structure-based catalyst screening iden...

K Sakthivel，W Notz，T Bui，... - 《Journal of the American Chemical Society》

Enantioselective organocatalytic Michael addition of malonate esters to nitro olefins using bifunctional cinchonine derivatives.

A family of 9-amino(9-deoxy) epicinchonine derivatives, possessing a range of mono- and bidentate hydrogen bond donor groups at the 9-position, were synthe...

Jinxing，Ye，J Darren，... - 《Chemical Communications》

Bifunctional thiourea-catalyzed enantioselective double Michael reaction of γ,δ-unsaturated β-ketoester to nitroalkene: asymmetric synthesis of ()-epiba...

The asymmetric synthesis of 4-nitrocyclohexanone derivatives has been accomplished by enantioselective double Michael additions of γ,δ-unsaturated β-ket...

Yasutaka，Hoashi，and，... - 《Tetrahedron Letters》