Dephosphorylation and activation of a p34cdc2/cyclin B complex in vitro by human CDC25 protein

OOCYTES arrested in the G2 phase of the cell cycle contain a p34 cdc2 /cyclin B complex which is kept in an inactive form by phosphorylation of its p34 cdc...

U Strausfeld，JC Labbé，D Fesquet，... - 《Nature》

cdc25 is a Specific Tyrosine Phosphatase That Directly Activates p34cdc - Jean Gautier, Mark J,

OOCYTES arrested in the G2 phase of the cell cycle contain a p34 cdc2 /cyclin B complex which is kept in an inactive form by phosphorylation of its p34 cdc...

J Gautier，MJ Solomon，RN Booher，...

Genetic control of cell division patterns in the Drosophila embryo

In Drosophila embryogenesis, mitotic control undergoes a significant transition during the 14th interphase. Mitoses before interphase 14 run on maternal pr...

 - 《Cell》

Regulatory phosphorylation of the p34cdc2 protein kinase in vertebrates.

The p34cdc2 protein kinase is a conserved regulator of the eukaryotic cell cycle. Here we show that residues Thr14 and Tyr15 of mouse p34cdc2 become phosph...

Norbury，Blow，Nurse - 《Embo Journal》

Inactivation of the p34cdc2-cyclin B complex by the human wee1 tyrosine kinase.

Examines the mechanisms that regulate progression through the eukaryotic cell cycle. Regulation of entry into mitosis in Schizosaccharomyces pombe by the w...

Parker，L Laura，Piwnica-Worms，... - 《Science》

The three postblastoderm cell cycles of Drosophila embryogenesis are regulated in G2 by string

The string (stg) locus of Drosophila encodes a factor that is thought to trigger mitosis by activating the p34 cdc2 protein kinase. stg is required for mit...

 - 《Cell》

The three postblastoderm cell cycles of Drosophila embryogenesis are regulated in G2 by string - ScienceDirect

The string (stg) locus of Drosophila encodes a factor that is thought to trigger mitosis by activating the p34 cdc2 protein kinase. stg is required for ...

BA Edgar，Patrick H. O&#x;Farrell

Dephosphorylation and activation of Xenopus p34cdc2 protein kinase during the cell cycle.

Genetic studies in the fission yeast Schizosaccharomyces pombe have established that a critical element required for the G2----M-phase transition in the ce...

J Gautier，T Matsukawa，P Nurse，... - 《Nature》

Human cdc2 protein kinase is a major cell-cycle regulated tyrosine kinase substrate

cdc2 is a catalytic subunit of a protein kinase complex, called the M-phase promoting factor, that induces entry into mitosis and is universal among eukary...

G Draetta，H Piwnica-Worms，D Morrison，... - 《Nature》

Coupling of mitosis to the completion of S phase in Xenopus occurs via modulation of the tyrosine kinase that phosphorylates p34cdc2.

In cell-free extracts derived from Xenopus eggs which oscillate between S phase and mitosis, incompletely replicated DNA blocks the activation of p34 cdc2 ...

C Smythe，JW Newport - 《Cell》