Total Synthesis of ??-Pyrone Meroterpenoids, Novel Bioactive Microbial Metabolites
摘要:
Bioactive natural products produced by microbes have limitless potential in pharmaceutical applications,and the organic synthesis of such products as lead compounds will result in the creation of new and widely useful pharmaceutical products.With a focus on the drug discovery process,the Kitasato Institute is using cutting-edge,unique screening techniques to discover useful bioactive natural products from microbial metabolites.These novel natural products have distinctive structures and attractive bioactivities.
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DOI:
10.1021/cr040628i
年份:
2006
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