Stereochemistry of the sn2′ displacement of chiral 1, 3-disubstituted bromoallenes to form chiral acetylenes

Optically active 1,3-disubstituted bromoallenes react with a variety of cuprate reagents preferentially in an S N2′ fashion with very high anti selectivity.

EJ Corey，NW Boaz - 《Tetrahedron Letters》

Stereoelectronic Control in Enolization-Ketonization Reactions1

The stereochemistry of the enolization of 3尾-acetoxycholestan-7-one to the 螖6-en-7-ol and of the ketonization of this enol have been studied using deuterium tracer. With hydrogen bromide as catalyst in chloroform solution the axial hyd...

EJ Corey，RA Sneen - 《Journal of the American Chemical Society》

Further Investigation of the Nature of the C‐Li Bond. Structures of a Phenylthiomethyllithium Complex and ofa Methylthiomethyllithium Complex

Phenylthiomethyllithium/ N , N , N ′, N ′-tetramethylethylenediamine (TMEDA) (1:1) is shown by X-ray analysis to be dimeric in the crystalline state. The structural unit contains a six-membered ring in which each Li is bonded to the te...

R Amsturz，T Laube，WB Schweizer，... - 《Helvetica Chimica Acta》

ChemInform Abstract: ALKYLATION OF ALLYLIC DERIVATIVES. 8. REGIO‐ AND STEREOCHEMISTRY OF ALKYLATION OF ALLYLIC CARBOXYLATES WITH LITHIUM METHYLCYANOCUPRATE

Bei der Behandlung mit dem Lithium-cuprat (II) erhlt man aus dem 2-Cyclohexenylacetat (I) die isome- ren Dimethyl-cyclohexene (III) und (IV).

HL Goering，SS Kantner - 《Chemischer Informationsdienst》

Chemistry of fission products in the primary system

Peraluminous magmas may be generated by a variety of mechanisms. Isotopic studies can provide strong constraints to be imposed on the processes involved. H...

DF Torgerson，F Garisto，N Garisto，... - Trans. Am. Nucl. Soc.; (United States)

The Chemistry of Carbanions. XII. The Role of Copper in the Conjugate Addition of Organometallic Reagents

The reaction of trans-3-penten-2-one (1) with methyllithium and with methylmagnesium has been studied to learn the effect of added copper salts on the reaction rate and the proportions of reaction products 3 and 4. These studies have led...

HO House，WL Respess，GM Whitesides - 《Journal of Organic Chemistry》

Stereospecific 1,4-additions of methyl cyanocuprate to enol phosphates of .alpha.,.beta.-epoxycyclohexanones: application to the total synthesis of (.+-.)-...

We examined two methods of combining catch-and-effort data from small geographic regions into large regulatory areas to estimate catch-per-unit-effort (CPU...

JP Marino，H Abe - 《Cheminform》

Chiral epoxides as precursors of chiral allenes

We have applied the Sharpless asymmetric epoxidation to allylic alcohols containing a conjugated alkyne. Reaction of dialkyl metallic cuprates with the res...

AC Oehlschlager，E Czyzewska - 《Chemischer Informationsdienst》

Solid state structure of [Au2Li2(C6H4CH2NMe2-2)4]. A model for the reactive structure of organocuprates

Universiteit Utrecht

G Van Koten，JTBH Jastrzebski，CH Stam，... - 《Journal of the American Chemical Society》

Carbon-carbon bond formation by selective coupling of n-alkylcopper reagents with organic halides

For the past fifty years, Professor Gary H. Posner has made a significant impact on the field of synthetic organic chemistry. This short review aims to briefly highlight just some of his major contributions, including: (1) early work in ...

EJ Corey，GH Posner - 《J.am.chem.soc》