The mammalian homologue of the avian bursa of Fabricius. II. Extirpation, lethal x-irradiation, and reconstitution in rabbits. Effects on humoral immune responses, immunoglobulins, and lymphoid tissues.
摘要:
The similarities between the gut-associated lymphoid tissue (GALT) of mammals and follicles of the avian bursa of Fabricius are reviewed and further investigated. Rabbits deprived of GALT were incapable of responding to a primary antigenic stimulation (Brucella abortus) but showed normal secondary responses (Br. abortus and sheep erythro-cytes). They failed to repopulate thymus-indepen-dent are...
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关键词:
antibodies antigens extirpation follicles globulins humoral immunity IgM immune competence immune response immunocompetent cells
被引量:
年份:
1970
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