USE OF ADIPOSE TISSUE-DERIVED STROMAL CELLS FOR CHONDROCYTE DIFFERENTIATION AND CARTILAGE REPAIR

Methods and compositions for directing adipose-derived stromal cells cultivated in vitro to differentiate into cells of the chondrocyte lineage are disclosed. The invention further provides a variety of chondroinductive agents which can ...

YDC Halvorsen，WO Wilkison，JM Gimble - US

Two-phase oxygenated solution and method of use

A two-phase mixture is provided having a dissolved gas and a suspension of bubbles in a liquid. Methods for making, maintaining, and using the two-phase mixture are also provided. The gas molecules may be introduced into the liquid at a ...

EC Eckert - US

CROSS PRIMINGAMPLIFICATION OF TARGET NUCLEIC ACIDS

Methods of amplifying target sequences by utilizing cross priming isothermal amplification are disclosed Methods of marking the amplification target sequence during the amplification reaction and rapid detection of the target sequence ar...

Q You - WO

Enzymatic demethylation of flavonoids

The invention discloses the demethylation of 5-methoxyflavonoids by bacterial enzymes, the use of these enzymes in the production of phytoestrogens in vitro, and in pharmaceutical compositions in combination with a source of methylated 5...

S Possemiers，W Verstraete，A Heyerick，... - US

mitotic kinase, NIMA, encoded by the Aspergillus nimA gene; pure WW domain of a Pin1 polypeptide which interacts with NIMA; a Peptidyl-prolyl cis/trans isomerases (PPIase); drug target; Pin1 is a PPIase known to be essential for life

A novel class of NIMA interacting proteins (PIN), exemplified by Pin1, is provided. Pin1 induces a G2 arrest and delays NIMA-induced mitosis when overexpressed, and triggers mitotic arrest and DNA fragmentation when depleted. Methods of ...

T Hunter，KP Lu - US

Dietary supplements for regulating the central nervous system

Compositions comprising a plurality of yeast cells, wherein said plurality of yeast cells have been cultured in the presence of an alternating electric field having a specific frequency and a specific field strength for a period of time ...

LY Cheung

OCHROBACTRUM SP. FOR DEGRADING TETRABROMOBISPHENOL-A (TBBPA) AND ITS APPLICATION

The invention discloses ansp. for degrading TBBPA and its application in environmental remediation. Ansp. for degrading TBBPA was isolated from the sludge ...

G Li，T An，L Zu

Genetic screen for bioactive peptides

A method of screening for a protein involved in the extracellular regulation of latent TGFβ activation by transducing a cell line with a retroviral cDNA library to create a reporter cell line that produces green fluorescent protein (GFP...

DB Rifkin，JS Munger，JP Annes - US

rbLIF PROTEIN FOR USE IN EMBRYONIC STEM CELL CULTURES

Provided herein methods of maintaining an embryonic stem cell culture in an undifferentiated state, wherein the method includes culturing an embryonic stem cell on a rabbit feeder cell layer, wherein the rabbit feeder layer expresses a l...

J Xu，J Yang，X Tian，...

CLOSED CELL CULTURE SYSTEM

An object of the present invention is to provide a tissue cell culture system whereby a call tissue can be efficiently and quickly proliferated in vivo and the onset bacterial infection in an injured part can be avoided in the course of ...

SUZUKI Shigeki - US