Proteins play a crucial role in life, taking part in all vital processes in the body. In the past decade, there was increasing interest in delivering activ...
The study of biological functions of proteins in cells as well as therapeutic exploration of many protein drugs demands efficient and nontoxic intracellula...
Herein, a series of biocompatible, robust, pH/sugar-sensitive, core-cross-linked, polyion complex (PIC) micelles based on phenylboronic acid-catechol inter...
The growing interest in therapeutic proteins for biomedical applications is still limited by their tendency to degrade and undergo opsonization when expose...
The use of multifunctional quantum dots (QDs) as smart nanocarriers has exhibited substantial promise for imaging, targeting and therapeutic functionalitie...
Encapsulating anticancer protein therapeutics in nanocarriers is an attractive option to minimize active drug destruction, increase local accumulation at d...
The application of nanotechnology in the field of drug delivery has attracted much attention in the latest decades. Recent breakthroughs on the morphology ...
Nanogels are swollen nanosized networks composed of hydrophilic or amphiphilic polymer chains. They are developed as carriers for the transport of drugs, a...
The development of protein-based vaccines remains a major challenge in the fields of immunology and drug delivery. Although numerous protein antigens have ...
The ability to target contrast agents and therapeutics inside cells is becoming important as we strive to decipher the complex network of events that occur...
Polycations that absorb protons in response to the acidification of endosomes can theoretically disrupt these vesicles via the "proton sponge" effect. To e...
Special delivery! Polyionic complex (PIC) micelles that contain the charge-conversional moieties citaconic amide or cis-aconitic amide were developed for c...
During encapsulation of proteins in biodegradable microspheres, a significant amount of the protein reportedly undergoes denaturation to form irreversible ...
The aim was to evaluate the potential of specific bioadhesive nanoparticles to increase the oral bioavailability of pre-systemic degraded drugs, using 5-fl...
Target proteins can be functionally encapsulated using a cocoon-like polymeric nanocapsule formed by interfacial polymerization. The nanocapsule is cross-l...
Polymeric carriers designed to encapsulate protein antigens have great potential for improving the efficacy of vaccines and immunotherapeutics for diseases...
