Physician's Desk Reference

Purpose: This study aims to investigate how gender-based differences are actually reflected on drug approval. Methods: Data on gender-based differences of ...

허정선，김경희，윤인경，...

An experiment to determine the active therapeutic moiety of sulphasalazine.

Sulphasalazine (S.A.S.P.) is of proven value in the treatment of ulcerative colitis, but its mode of action is unknown. When it is taken by mouth, nearly a...

AKA Khan，J Piris，SC Truelove - 《Lancet》

Prostaglandin synthesis inhibitors in ulcerative colitis: flurbiprofen compared with conventional treatment.

It has been suggested that prostaglandins (PGs) play a pathogenetic role in ulcerative colitis (UC) and that treatment with inhibitors of PG synthesis might be of therapeutic benefit. We therefore performed a one-week open trial to compa...

DS Rampton，GE Sladen - 《Prostaglandins》

Book Reviews: The Theory and Practice of Industrial Pharmacy

In the present investigation, Sepharose 6B gel with 1,4-butanediol diglycidyl ether as spacer arm, iminodiacetic acid as the ligand and Cu2+, Ni2+ as metal ions were used to prepare an immobilized metal ion affinity (IMA) gel. The bindin...

LD King - 《Journal of Clinical Pharmacology》

Studies of prostaglandins and sulphasalazine in ulcerative colitis

Specific evidence is presented of the release of prostaglandins from the colon in active ulcerative colitis. An increase in the levels of bioassayed prostaglandin-like activity in the stools and colo-rectal venous plasma from patients wi...

SR Gould，AR Brash，ME Conolly，... - 《Prostaglandins Med》

Friable tablet and process for manufacturing same

1. A pressed medicinal tablet which is resistant to breakage and chipping under impact but is capable of being crushed and disintegrated by the pressure of the thumb, said tablet being composed of about 30 to 70% by weight of hard, spher...

BR Henry - US

2-Hydroxy-5-phenylazobenzoic acid derivatives and method of treating ulcerative colitis therewith

The present invention provides a pharmaceutical composition for treating ulcerative colitis containing at least one compound of the general formula: ##STR1## wherein X is an --SO 2 -- or --CO-- group and R is either an unsubstituted or ...

RPK Chan - US

Topical treatment of distal ulcerative colitis with 4-amino-salicylic acid enemas.

Enemas of 4-amino-salicylic acid (4-ASA) have been compared with placebo enemas in a double-blind study for the treatment of distal ulcerative colitis of m...

WS Selby，MK Bennett，DP Jewell - 《Digestion》

Orally administrable pharmaceutical composition

A solid dosage form, such as a capsule or tablet, containing a pharmacologically active agent is coated with an anionic polymer, which is insoluble in gastric juice and in intestinal juice below pH7 but soluble in colonic intestinal juic...

J Rhodes，BK Evans - CA

Disodium cromoglycate in the treatment of ulcerative colitis and Crohn's disease.

A controlled clinical study on disodium cromoglycate (DSCG) at a dose of 800 mg per day versus placebo was carried out in 141 patients with ulcerative coli...

V Binder，L Elsborg，J Greibe，... - Gut