New methods of drug delivery
Conventional forms of drug administration generally rely on pills, eye drops, ointments, and intravenous solutions. Recently, a number of novel drug delive...
Langer，R - 《Science》
DERIVATIVES OF TAXOL, PHARMACEUTICAL COMPOSITIONS THEREOF AND METHODS FOR THE PREPARATION THEREOF
the invention relates to derivatives of taxol, represented by the formula (ii), wherein r and r 'are each h or is an amino acid selected from the group consisting of alamine, leucine, isoleucine, phenylalanine, proline, salt, lysine and ...
VJ Stella，AE Mathew - WO
Controlled drug delivery using polymer/pluronic blends
A new series of degradable polymeric matrices were prepared by blending polymers that degrade by hydrolysis such as poly(L-lactic acid)(PLA), and nonionic Pluronic surfactants, block copolymers of polyethyleneoxide (PEO) and polypropylen...
TG Park，S Cohen，RS Langer - US
Biodegradable Poly(Lactic Acid) and Poly (Lactide-Co-Glycolide) Polymers in Sustained Drug Delivery
Poly(lactic acid) [PLA] and its co-polymers with glycolic acid [PLCG] have been known for the past 20 years of its biodegradability and histocompatibility....
RU Jalil - 《Drug Development Communications》
Synthetic polymers in modern pharmacy
; Dep. sci. industrial res., chemistry div., Wellington, NOUVELLE-ZELANDE PRPSB8 1989,vol.14,n5,pp.629-677(352 ref.)AnglaisElsevier, Kidlington, ROYAUME-UNI (1967) (Revue); ; ; ; ; ; ; ; ; INIST-CNRS, Cote INIST : 9063
WJ Passl - 《Progress in Polymer Science》
Method of delivering micellular particles encapsulating chemotherapeutic agents to tumors in a body
A method is provided for delivering micellular particles containing chemotherapeutic agents and a marker to tumors within a body for the diagnosis and treatment of such tumors. The micellular particles are small, less than 2000 and inco...
CA Presant，RT Proffitt，RL Teplitz，... - 《Biotechnology Advances》
Flexible, finite, bioadhesive, therapeutical agent in solid form
Compositions for topical application comprising a therapeutically effective amount of a pharmaceutical agent(s), a pharmaceutically acceptable carrier, and...
JA Mantelle - US
Physical trapping type polymeric micelle drug preparation
The present invention relates to drug carriers composed of a block copolymer having hydrophilic and hydrophobic segments, a polymeric micelle type drug comprising hydrophobic drugs trapped by physical treatments in said drug carrier and ...
M Yokoyama，Y Sakurai，T Okano，... - US
A COMPOSITION CONTAINING A TETRACYCLINE AND USE FOR INHIBITING ANGIOGENESIS
Pharmaceutical compositions for delivering an effective dose of an angiogenesis inhibitor consisting of a tetracycline or tetracycline such as minocycline. The effective dosage for inhibition of angiogenesis based on in vitro testing is ...
HENRY BREM，RAFAEL J TAMARGO，ROBERT A BOK
Biodegradable poly(lactic acid) and poly(lactide-co-glycolide) microcapsules: problems associated with preparative techniques and release properties
Poly(lactic acid) [PLA] and its co-polymers with glycolic acid [PLCG] have been known to be biodegradable and histocompatible for the past 20 years. Their ...
R Jalil，JR Nixon - 《Journal of Microencapsulation》
