Anti-angiogenic compositions and methods of use
The present invention provides compositions comprising an anti-angiogenic factor, and a polymeric carrier. Representative examples of anti-angiogenic facto...
Também publicado como US5716981 , US5994341 , US20020165265
GELS FOR ENCAPSULATION OF BIOLOGICAL MATERIALS
This invention provides novel methods for the formation of biocompatible membranes around biological materials using photopolymerization of water soluble molecules. The membranes can be used as a covering to encapsulate biological materi...
JA Hubbell,CP Pathak,AS Sawhney,... - US
PROTEIN STABILIZED PHARMACOLOGICALLY ACTIVE AGENTS, METHODS FOR THE PREPARATION THEREOF AND METHODS FOR THE USE THEREOF
In accordance with the present invention, there are provided compositions and methods useful for the in vivo delivery of substantially water insoluble pharmacologically active agents (such as the anticancer drug paclitaxel) in which the ...
DESAI Neil P.,TAO Chunlin,YANG Andrew,... - US
Anti-angiogenic compositions and methods of use
The present invention provides compositions comprising an anti-angiogenic factor, and a polymeric carrier. Representative examples of anti-angiogenic factors include Anti-Invasive Factor, Retinoic acids and derivatives thereof, and pacli...
Hunter, William L,Machan, Lindsay S,Arsenault, Larry A
Polymeric shells for medical imaging prepared from synthetic polymers, and methods for the use thereof
In accordance with the present invention, compositions comprising imaging agent(s) contained within polymeric shells are provided. Invention compositions are useful, for example, as contrast agents for magnetic resonance imaging (MRI), u...
Mark W. Grinstaff,Neil P. Desai,Kenneth S. Suslick,... - Elsevier BV
Method for the preparation of fluorocarbon-containing polymeric shells for medical imaging
In accordance with the present invention, compositions comprising imaging agent(s) contained within polymeric shells are provided. Invention compositions are useful, for example, as contrast agents for magnetic resonance imaging (MRI), u...
MW Grinstaff,NP Desai,KS Suslick,... - US
Injectable compositions, nanoparticles useful therein, and process of manufacturing same
Particles in the size range from about 10 to about 1000 nm, preferably less than about 500 nm, which comprise a crosslinked matrix of macromolecules of natural origin.A biologically or pharmacodynamically active material may be supported...
RC Oppenheim,JJ Marty,P Speiser - US
Coacervate-based matrix containing medicament in encapsulated film; surface active phospholipids
Drug delivery compositions yeild new and unexpected degrees of stabilization, solubilization and delivery of incorporated medicaments, drugs, or other phys...
B Ecanow
Methods for in vivo delivery of nutriceuticals and compositions useful therefor
In accordance with the present invention, there are provided compositions useful for the in vivo delivery of a biologic, wherein the biologic is associated with a polymeric shell formulated from a biocompatible material. The biologic can...
MW Grinstaff,P Soon-Shiong,M Wong,... - US
Composition useful for in vivo delivery of biologics and methods employing same
In accordance with the present invention, there are provided compositions useful for the in vivo delivery of a biologic, wherein the biologic is associated with a polymeric shell formulated from a biocompatible material. The biologic can...
MW Grinstaff,P Soon-Shiong,M Wong,... - US