Method of encapsulating biologically active materials in multilamellar lipid vesicles (MLV)
申请(专利)号：
US19820432686
申请日期：
1982-10-04
公开/公告号：
US4485054A
公开/公告日期：
1984-11-27
申请(专利权)人：
LIPODERM PHARMACEUTICALS LIMITED
被引量：
摘要：
This invention provides an improved procedure for producing large multilamellar lipid vesicles (MLV), which may be used to encapsulate a biologically active material, particularly lipophilic substances. According to this invention, a lipid film is formed on inert, solid contact masses within a vessel, by evaporating an organic solvent therefrom. Subsequent agitation in the presence of an aqueous liquid, followed by a period in which the vessel remains undisturbed yields the multilamellar vesicles. The procedure permits the encapsulation of both hydrophilic and lipophilic materials.
展开
通过文献互助平台发起求助，成功后即可免费获取论文全文。
相似文献
参考文献
引证文献
辅助模式
引用
文献可以批量引用啦~
欢迎点我试用！
