Method of binding collagen recognizing substances to liposomes
申请(专利)号:
CA19952176566
申请日期:
1995-10-03
公开/公告号:
CA2176566A1
公开/公告日期:
1996-04-11
申请(专利权)人:
BAXTER INTERNATIONAL INC.
被引量:
摘要:
Recognizing substances, including epidermal growth factor, gelatin, collagen and hyaluronic acid, have been covalently bound to liposomal surfaces and utilized to attach liposomes onto a cellular or an extracellular matrix (ECM) target site. These bioadhesive liposomes offer several advantages including the mutual protection of both the drug and biological environment; an increase in drug bioavailability and retention at the target site; and improved adherence or adhesion to the designated target site.
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