Surface modified drug nanoparticles

 - US

Surface modified drug nanoparticles

Dispersible particles consisting essentially of a crystalline drug substance having a surface modifier adsorbed on the surface thereof in an amount sufficient to maintain an effective average particle size of less than about 400 nm, meth...

GG Liversidge，KC Cundy，JF Bishop，... - EP

Surface modified anticancer nanoparticles

Dispersible particles consisting essentially of a crystalline anticancer agent having a surface modifier adsorbed on the surface thereof in an amount sufficient to maintain an effective average particle size of less than about 1000 nm. A...

GG Liversidge，E Liversidge，PP Sarpotdar - US

Characterization of Fluids from the Stomach and Proximal Jejunum in Men and Women

Purpose . To chemically characterize the fluids available for drug dissolution in the upper gastrointestinal tract during the fasted state in humans, and t...

A Lindahl，AL Ungell，L Knutson，... - 《Pharmaceutical Research》

Physical properties of solid molecular dispersions of indomethacin with poly(vinylpyrrolidone) and poly(vinylpyrrolidone-co-vinyl-acetate) in relation to i...

PURPOSE: To measure solid-state features of amorphous molecular dispersions of indomethacin and various molecular weight grades of poly(vinylpyrrolidone), ...

T Matsumoto，G Zografi - 《Pharm Res》

Physical Properties of Solid Molecular Dispersions of Indomethacin with Poly(vinylpyrrolidone) and Poly(vinylpyrrolidone-co-vinyl-acetate) in Relation to I...

Purpose. To measure solid-state features of amorphous molecular dispersions of indomethacin and various molecular weight grades of poly(vinylpyrrolidone), ...

MG Zografi - 《Pharmaceutical Research》

Physical properties of solid molecular dispersions of Indomethacine with PVP and PVPVA in relation to Indomethacine recrystallization

To measure solid-state features of amorphous molecular dispersions of indomethacin and various molecular weight grades of poly(vinylpyrrolidone), PVP, and ...

T Matsumoto，G Zografi - 《Pharmaceutical Research》

Novel formulations of pharmacological agents, methods for the preparation thereof and methods for the use thereof

In accordance with the present invention, there are provided compositions and methods useful for the in vivo delivery of substantially water insoluble pharmacologically active agents (such as the anticancer drug paclitaxel) in which the ...

NP Desai，Soon-shiong, Patrick，S Magdassi，... - EP

DHA-pharmaceutical agent conjugates of taxanes

The invention provides conjugates of cis-docosahexaenoic acid and taxanes useful in treating cell proliferative disorders. Conjugates of paclitaxel and docetaxel are preferred.

VE Shashoua，CE Swindell，NL Webb，... - US

Surface modified anticancer nanoparticles

Dispersible particles consisting essentially of a crystalline anticancer agent having a surface modifier adsorbed on the surface thereof in an amount sufficient to maintain an effective average particle size of less than about 1000 nm. A...

GG Liversidge，E Liversidge，PP Sarpotdar - US