Transmucosal delivery
摘要：
Compositions and methods of manufacture for producing a medicament composition capable of absorption through the mucosal tissues of the mouth, pharynx, and esophagus. The present invention relates to such compositions and methods which are useful in administering drugs in a dose-to-effect manner such that sufficient drug is administered to produce precisely a desired effect. The invention also relates to a manufacturing technique that enables a therapeutic agent or drug to be incorporated into a flavored confectionary base and to compress or otherwise attach the solid confectionary mixture onto an appliance or holder. Employing the present invention, the drug may be introduced into the patient's bloodstream almost as fast as through injection, and much faster than using the oral administration route, while avoiding the negative aspects of both of these methods. The present invention achieves these advantages by incorporating the drug into a compressed powder "candy " matrix. The pH and pKa of the powder matrix can be modified to increase the absorption of the drug through the mucosal tissues.
展开
通过文献互助平台发起求助，成功后即可免费获取论文全文。
相似文献
参考文献
引证文献
研究点推荐
站内活动
辅助模式
引用
文献可以批量引用啦~
欢迎点我试用！
