Replication-incompetent adenoviral vaccine vector elicits effective anti-immunodeficiency-virus immunity.

Elsevier's Scopus, the largest abstract and citation database of peer-reviewed literature. Search and access research from the science, technology, medicin...

JW Shiver，TM Fu，L Chen，... - 《Nature》

A component of innate immunity prevents bacterial biofilm development.

Examines the importance of antimicrobial factors of innate immunity in the prevention of biofilm and bacterial infections. Ability to kill bacteria deposit...

MR Parsek，EP Greenberg，MJ Welsh，... - 《Nature》

Stratification of Type 1 Diabetes Risk on the Basis of Islet Autoantibody Characteristics

Despite the excellent overall prognosis, unpredictable breast cancer recurrences and deaths also occur among T1N0M0 patients. We have evaluated clinically ...

P.，Achenbach，K.，... - 《Diabetes》

Satisfaction (not) guaranteed: re-evaluating the use of animal models of type 1 diabetes

Without a doubt, rodent models have been instrumental in describing pathways that lead to pancreatic beta-destruction, evaluating potential causes of and p...

BO Roep，M Atkinson，MV Herrath - 《Nature Reviews Immunology》

Blood and islet phenotypes indicate immunological heterogeneity in type 1 diabetes.

Studies in type 1 diabetes indicate potential disease heterogeneity, notably in the rate of β-cell loss, responsiveness to immunotherapies, and, in limite...

S Arif，P Leete，V Nguyen，... - 《Diabetes》

Is my sick child healthy? Is my healthy child sick?: Changing parental experiences of cystic fibrosis in the age of expanded newborn screening

This paper explores how rapid growth in the USA of mandatory newborn screening (NBS) leading to a diagnosis of cystic fibrosis is changing, for affected fa...

R Grob - 《Social Science & Medicine》

Glycosylation of type II collagen is of major importance for T cell tolerance and pathology in collagen-induced arthritis.

TypeII collagen (CII) is a candidate cartilage-specific autoantigen, which can become post-translationally modified by hydroxylation and glycosylation. T c...

J B?Cklund，A Treschow，R Bockermann，... - 《European Journal of Immunology》

NKT and T cells: coordinate regulation of NK-like phenotype and cytokine production.

A maturation-dependent change in phenotype and cytokine production from relatively immature CD161– or CD161+, IL-13+IL-4+, IFN-γ–, to mature CD161+CD56+...

M Loza，L Metelitsa，B Perussia - 《European Journal of Immunology》

Rituximab does not reset defective early B cell tolerance checkpoints

Type 1 diabetes (T1D) patients show abnormalities in early B cell tolerance checkpoints, resulting in the accumulation of large numbers of autoreactive B c...

Nicolas，Chamberlain，Christopher，... - 《Journal of Clinical Investigation》

TRAIL Modulates the Immune System and Protects against the Development of Diabetes

TRAIL or tumor necrosis factor (TNF) related apoptosis-inducing ligand is a member of the TNF superfamily of proteins, whose best characterized function is...

B Fleur，B Stella，Z Giorgio，... - 《Journal of Immunology Research》