Inhibition of HIV-1 Replication by Isoxazolidine and Isoxazole Sulfonamides

Targeting host factors is a complementary strategy for the development of new antiviral drugs. We screened a library of isoxazolidine and isoxazole sulfona...

B Loh，L Vozzolo，BJ Mok，... - 《Chemical Biology & Drug Design》

Preparation and crystal structures of two 3‐anthracenyl isoxazolyl sulfonamides

Structures of isoxazole sulfonamides ( 3a ) and ( 5a ), were obtained as the SR/RS-diastereomer, however, studies indicate that this is a consequence...

C Li，B Twamley，NR Natale - 《Journal of Heterocyclic Chemistry》

Synthesis of functionally substituted isoxazoles from 5-(2,5-dimethylphenyl)-1,2-oxazole-3-carbonitrile

Sulfonamides and urea derivative containing 5-(2,5-dimethylphenyl)isoxazole fragments were synthesized.doi:10.1134/S107042800906013XV. I. Potkin...

VI Potkin，SK Petkevich，EG Zalesskaya - 《Russian Journal of Organic Chemistry》

Green synthesis and anti-biofilm activities of 3,5-disubstituted isoxazoline/isoxazole-linked secondary sulfonamide derivatives on Pseudomonas aeruginosa

We report herein the synthesis and characterization of a new series of 13 molecules combining isoxazoline/isoxazole sulfonamides and hydrazides motives. These ...

A El Mahmoudi，AS Tareau，M Barreau，... - 《Bioorganic & Medicinal Chemistry Letters》

SUBSTITUTED BIPHENYL ISOXAZOLE SULFONAMIDES AS DUAL ANGIOTENSIN ENDOTHELIN RECEPTOR ANTAGONISTS

The present invention provides N-isoxazolyl biphenyl sulfonamide compounds of Formula (I), wherein R¹, R², R³, R⁴, and R⁵ are as defined herein. These compounds are dual angiotensin ...

MURUGESAN NATESAN，EWING WILLIAM，GU ZHENGXIANG，... - WO

SUBSTITUTED BIPHENYL ISOXAZOLE SULFONAMIDES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM

The present invention relates to compounds of formula I wherein X and Y are nitrogen and the other is oxygen; R1, R2, R3 and R4 are each independently hydr...

JC Barrish，N Murugesan