The functional significance, distribution, and structure of LFA-1, LFA-2, and LFA-3: cell surface antigens associated with CTL-target interactions.
Three cell surface antigens associated with the cytolytic T lymphocyte(CTL)-target cell interaction were identified by generation of monoclonal antibodies (MAb) against OKT4+, HLA-DR-specific CTL and selection for inhibition of cytolysis...
AM Krensky,F Sanchez-Madrid,E Robbins,... - 《Journal of Immunology》
NK CELL RECEPTORS - Annual Review of Immunology, 16(1):359
NK cells are regulated by opposing signals from receptors that activate and inhibit effector function. While positive stimulation may be initiated by an array of co-stimulatory receptors, specificity is provided by inhibitory signals tra...
LL Lanier - 《Nk Cells Mhc Class I Kir Ly49 Tyrosine Phosphatase》
The making of strand-specific M13 probes
A novel approach has been developed for the preparation of highly radioactive, strand-specific M13 probes. A universal primer, complementary to the region ...
H Nien-Tai,J Messing - 《Gene》
Identification of a human T lymphocyte surface protein associated with the E-rosette receptor.
We describe a new monoclonal murine antibody that reacts with a 50,000-mol wt polypeptide that appears to be present on all E-rosetting cells. We conclude that this antigen is either identical to or closely associated with the E receptor...
Kamoun,M. - 《Journal of Experimental Medicine》
A DC-specific cytolytic T lymphocyte line is OKT8+1
A human cytotoxic T lymphocyte (CTL) line, A9, was generated by limiting dilution and was selected because of its apparent DC specificity. A9 is 100% OKT3+, 90% OKT4+, and 10% OKT8+, but by negative selection the CTL present are entirely...
AM Krensky,C Clayberger,JL Greenstein,... - 《Journal of Immunology》
Deficient natural killer cell activity in x-linked lymphoproliferative syndrome
The activity of natural killer cells was found to be deficient in 10 of 12 males with X-linked lymphoproliferative syndrome, a life-threatening proliferati...
J Sullivan,K Byron,F Brewster,... - 《Science》
Phytohaemagglutinin activation of T cells through the sheep red blood cell receptor
Expression of receptors for sheep red blood cells and the ability to proliferate in response to phytohaemagglutinin (PHA) are the traditional properties of human T cells 1,2 , but the function of the sheep red cell receptor (the T11 anti...
- 《Nature》
Short-term, high-efficiency expression of transfected DNA.
We have achieved high-efficiency uptake and expression of foreign DNA in mouse Ltk- cells by modifying the DEAE-dextran-mediated transfection method of McC...
DJ Sussman,G Milman - 《Molecular & Cellular Biology》
High-Frequency Transfer ofCloned HerpesSimplex Virus Type1Sequences toMammalianCells byProtoplast Fusion
The protoplast fusion technique of Schaffner (W. Schaffner, Proc. Natl. Acad. Sci. U.S.A. 77:2163-2167, 1980) has been adapted to introduce cloned herpes simplex virus genes into cultured mammalian cells. The technique involves digesting...
RM Sandri-Goldin,AL Goldin,M Levine - 《Molecular & Cellular Biology》
Krensky AM, Sanchez-Madrid F, Robbins E, Nagy JA, Springer TA, Burakoff SJThe functional significance, distribution, and structure of LFA-1, LFA-2, and LFA...
Three cell surface antigens associated with the cytolytic T lymphocyte(CTL)-target cell interaction were identified by generation of monoclonal antibodies ...
AM Krensky,FW Sanchez-Madrid,E Robbins,... - 《Journal of Immunology》