Catalytic asymmetric induction. Highly enantioselective addition of dialkylzincs to aldehydes.

Addition of catalytic amounts of the optically active amino alcohol (I) to the reaction of (II) with (III) or (V) gives the (S)-alcohols (IV) and (VI) in h...

M Kitamura，S Suga，K Kawai，... - 《Cheminform》

ChemInform Abstract: Chiral Alkoxytitanium(IV) Complexes for Enantioselective Nucleophilic Additions to Aldehydes and as Lewis Acids in Diels-Alder Reactions

A number of 1,4-diols such as (I), (II), 1,3-diols (III), (IV), and 1,2-diols (V), (VI) are prepared by conventional methods and used as alkoxy ligands on ...

D Seebach，AK Beck，R Imwinkelried，... - 《Cheminform》

Diastereoselective Hydroxyalkylation of the 1Position of 2-Pivaloyl 1,2,3,4-tetrahydroisoquinoline via Magnesium Derivatives

The first diastereoselective synthesis of the hydroxyamides 2 has been achieved using the magnesium reagent 1 and aldehydes. Acid-catalyzed rearrangement of 2, R = Ph, leads, depending on the conditions, cleanly to l- or u-amino esters 3...

D Seebach，DCMA Syfrig - 《Angewandte Chemie International Edition》

Asymmetric induction catalyzed by conjugate bases of chiral proton acids as ligands: Enantioselective addition of dialkylzinc-orthotitanate complex to benz...

The addition of diethylzinc-orthotitanate complex to benzaldehyde catalyzed by 0.0001∼0.04 equiv of chiral sulfonamide-titanate complex in toluene at 0...

Masato，Yoshioka，and，... - 《Tetrahedron Letters》

Some recent advances in the use of titanium reagents for organic synthesis

Only a few new results done in the laboratory of the authors are mentioined. The material may be divided into four groups: allylic triphenoxy-titanium reag...

D Seebach，AK Beck，M Schiess，... - 《Pure & Applied Chemistry》

The asymmetric hydrocyanation of aldehydes with cyanotrimethylsilane promoted by a chiral titanium reagent.

The asymmetric hydrocyanation of aldehydes with cyanotrimethylsilane proceeds by the use of a chiral alkoxy titanium(IV) to give the corresponding cyanohydrins with good enantioselectivity.

K Narasaka，T Yamada，H Minamikawa - 《Chemistry Letters》

Selective clathrate inclusion of primary and secondary amines in a new host series. Crystallographic reasoning of the inclusion behaviour

Representatives of the tartaric acid derived host compounds (1)–(3) are demonstrated to act as highly selective clathrate hosts for primary and secondary amines; this is supported by crystallographic evidence in three cases.

E Weber，I Goldberg - 《Journal of the Chemical Society Chemical Communications》

Catalytic asymmetric induction. Highly enantioselective addition of dialkylzincs to aldehydes

Representatives of the tartaric acid derived host compounds (1)–(3) are demonstrated to act as highly selective clathrate hosts for primary and secondary amines; this is supported by crystallographic evidence in three cases.

Masato.，Kitamura，Seiji.，... - 《Journal of the American Chemical Society》

Asymmetric synthesis of isoquinoline alkaloids by homogeneous catalysis

Efficient asym.

R Noyori，M Ohta，Y Hsiao，... - 《Journal of the American Chemical Society》

Enantioselective addition of dialkylzincs to aldehydes promoted by chiral amino alcohols. Mechanism and nonlinear effect

A new perspective on traditional energy minimization problems is provided by a connection between statistical thermodynamics and combinatorial optimization...

M Kitamura，S Okada，S Suga，... - 《Cheminform》