The Ras superfamily of GTPases is a family of monomeric molecular switches that regulate a variety of cellular processes, such as proliferation, migration,...
Hall A. G proteins and small GTPases: distant relatives keep in touch. Science. 1998;280:2074-5.Hall, A. (1998). G proteins and small GTPases: distant relatives keep in touch. Science OUM, 2074-2075...
The complement and immunoglobulin receptors are the major phagocytic receptors involved during infection. However, only immunoglobulin-dependent uptake res...
Induction of protein kinase C (PKC) pathway in the vascular tissues by hyperglycemia has been associated with many of the cellular changes observed in the ...
We studied the occurrence of renal disease by measuring serum creatinine and urine protein concentrations in the diabetic members of 316 Pima Indian famili...
Three members of the Rho family, Cdc42, Rac, and Rho are known to regulate the organization of actin-based cytoskeletal structures. In Bac1.2F5 macrophages...
tivation of PI 3-kinase could then serve to eliminate a Vav inhibitor and simultaneous- ly produce activators of Vav GEF activity. Vav is a member of a large family of mole- cules containing a Dbl homology domain and a PH domain that cou...
The organization of the actin cytoskeleton can be regulated by soluble factors that trigger signal transduction events involving the Rho family of GTPases....
Adhesion of tumor cells to host cell layers and subsequent transcellular migration are pivotal steps in cancer invasion and metastasis. The small GTPase Rh...
Hyperglycemia rapidly induces an increase in intracellular advanced glycation end products (AGEs) in bovine endothelial cells, causing an alteration in bFG...
Preβ HDL are small, protein rich lipoproteins that are predominantly composed of apo A-I, without apo A-II. Preβ HDL are secreted from the liver as nasce...
BACKGROUND: . Integrins induce the formation of large complexes of cytoskeletal and signaling proteins, which regulate many intracellular processes. The ac...
