Thiamin production by fermentation
Thiamin production by fermentation.The present invention provides a method for producing thiamin products using a microorganism containing a mutation that causes it to overproduce and release thiamin products into the medium. Biologicall...
Goese, Markus G，Perkins, John B，Schyns, Ghislain
Synthesis of locked nucleic acid derivatives
The invention relates to a novel strategy for the synthesis of Locked Nucleic Acid derivatives, such as α- L -oxy-LNA, amino-LNA, α- L -amino-LNA, thio-LNA, α- L -thio-LNA, seleno-LNA and methylene LNA, which provides scalable high yi...
M Detlef Sorensen，J Wengel，T Koch，... - US
USE OF POTENT, SELECTIVE AND NON TOXIC C-KIT INHIBITORS FOR TREATING INTERSTITIAL CYSTITIS
The present invention relates to a method for treating interstitial cystitis, comprising administering a tyrosine kinase inhibitor to a human in need of su...
MOUSSY Alain，KINET Jean-Pierre - WO
Genetic Alterations Associated with Autism and the Autistic Phenotype and Methods of Use Thereof for the Diagnosis and Treatment of Autism
Compositions and methods for the detection and treatment of autism and autistic spectrum disorder are provided.
H Hakonarson，J Glessner，J Bradfield，... - CA
Scanning analyzer for single molecule detection and methods of use
The invention encompasses analyzers and analyzer systems that include a single molecule analyzer, methods of using the analyzer and analyzer systems to analyze samples, either for single molecules or for molecular complexes. The single m...
R Livingston - US
Aldehyde detection kit and method thereof
The present application describes a reagent system for detecting presence of aldehyde in a sample that includes (i) Component A, which includes bisulfite, pararosalinine, and hydrochloric acid; and (ii) Component B, which includes a solu...
MJ Yoon，JC Lee，YS Ku - US
COMPOSITIONS AND METHODS FOR SPECIFIC CLEAVAGE OF EXOGENOUS RNA IN A CELL
There are provided compositions for cleaving an exogenous RNA of interest only in the presence of an endogenous signal RNA sequence, thereby activating expression of a polynucleotide of interest only in the presence of the endogenous sig...
A Guy - EP
GENE DEFECTS AND MUTANT ALK KINASE IN HUMAN SOLID TUMORS
In accordance with the invention, novel gene deletions and translocations involving chromosome 2 resulting in fusion proteins combining part of Anaplastic Lymphoma Kinase (ALK) kinase with part of a secondary protein have now been identi...
K Rikova，H Haack，L Sullivan，... - EP
PCR-Based Kit For Detecting Chlamydia Trachomatis and Nelsseria Gonorrhoeae
The invention relates to a PCR based prototype kit for detecting and comprising: a transport medium for sample collection solution A and B, a reaction mixture having the primer for and , a gel loading dye, Agarose gel, gel running buffer...
D Saluja，U Chaudhary，M Ali，... - US
Method for making derivatized guar gum and derivatized guar gum made thereby
A method for making a derivatized guar, comprising: (a) contacting derivatized guar splits, which have not been treated with a boron compound to crosslink the guar splits, with an aqueous wash medium comprising, based on 100 parts by wei...
S Krishnamurthy，K Luczak - US
