Light detecting optical device

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申请(专利)号：

09/646031

申请日期：

01/11/2001

公开/公告号：

US6714297

公开/公告日期：

03/30/2004

申请(专利权)人：

RUCKSTUHL THOMAS SEEGER STEFAN

发明人：

T Ruckstuhl，S Seeger

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摘要：

A fluorescing molecule is bound to an microscopic slide ( 24 ). The microscopic slide ( 24 ) is coupled to a first end face of an optical waveguide ( 1 ) by means of an immersion oil. The optical waveguide also possesses a shell surface ( 3 ) having the shape of a paraboloid of revolution, and a second end face ( 4 ). The molecule is located at the focal point of the paraboloid of revolution. Essentially the entire light of the molecule radiated into the half-space facing the optical waveguide ( 1 ) enters the optical waveguide ( 1 ). In particular, evanescent radiation ( 7 ) also enters the optical waveguide ( 1 ). This is totally internally reflected at the shell surface ( 3 ) having the shape of a paraboloid of revolution, emerges collimated from the second end face ( 4 ), and reaches a detector ( 30 ). In this way, essentially the entire evanescent radiation of the molecule can be registered. The optical arrangement thus improves the light-collecting efficiency for evanescent radiation, and thus the selective sensitivity of detection for molecules near the surface for fluorescence-based biosensors.

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