Generalized cytometry instrument and methods of use
申请(专利)号:
US06/577448
申请日期:
19840206
公开/公告号:
US04647531A
公开/公告日期:
19870303
申请(专利权)人:
ORTHO DIAGNOSTIC SYSTEMS INC.
被引量:
摘要:
A generalized cytometry instrument for measuring the kinetic properties of live cells. Cells are immobilized on a surface and their positions determined and stored in memory by a central control computer. The cells are subsequently illuminated and an optical interaction detected. By taking many measurements of many cells, each of whose position and respective data is stored permitting subsequent reexamination and determination of activity as a function of time, respectively; the kinetic properties of large populations of cells may be studied in the presence of a variety of stimulating environments. Such stimulations may arise from contact with various reagents, including antigens, mitogens and peptides as well as electrical and mechanical perturbations.
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