Buccal formulation

A buccal formulation for administering a medicament includes about 1- 20% by weight of a soluble, pharmaceutically acceptable adhesive, about 1- 10% by weight of a pharmaceutically acceptable disintegrant and a soluble, directly compress...

CH Hsiao，JL Cacace - US

Use of carbomer in controlled-release formulations to enhance or increase the dissolution rate of poorly soluble pharmacologically active substances

A method of preparing the formulation is also provided.

BW Barry，BA Mulley，P York - EP

BUCCAL FORMULATION

A buccal formulation for administering a medicament includes about 1-20% by weight of a soluble, pharmaceutically acceptable adhesive, optionally up to about 10% by weight of a pharmaceutically acceptable disintegrant and a soluble, dire...

CH Hsiao，JL Cacace，JA Mccarty - WO

Drug delivery system

A controlled release formulation comprising an adsorbate of a mixture of a pharmaceutically useful active ingredient and an inactive substance adsorbed on a cross-linked polymer. The inactive substance is selected to modify the dissoluti...

S Mulligan，RT Sparks - EP

A 6-0-methylerythromycin A derivative

A 6-O-methylerythromycin A derivative represented by the formula and the salts thereof are useful as intermediates for the preparation of 6-0-methylerythromicyn A and are themselves useful as antibiotics.

M Shigeo，A Takashi，A Toshifumi，... - EP

Erythromycin formulations for oral administration

Improved oral formulations for the administration of erythromycin and its derivatives are provided. An oil solution, suspension or emulsion of the erythromycin or derivative, in combination with N-methyl-2-pyrrolidone in a soft gelatin c...

AL Adjei，MK Vadnere，HS Cheskin - EP

Stable erythromycin solution and process therefor

A pharmaceutical formulation comprising per ml. from 1 to 100 mg. of the active ingredient erthromycin and the excipients ethanol, sufficient non-toxic acid to give a pH in the range of 8-10 after dilution with water, and propylene glyco...

T Harun，CJ Ellen - EP

An erythromycin compound, a process for preparing the compound and compositions containing the compound useful in the treatment of acne

Zinc erythromycin is prepared by reacting zinc salts, especially zinc carboxylates, with an erythromycin. Compositions containing zinc erythromycin are useful for the topical treatment of acne. The compositions are preferably free of wat...

LW Louis，WR Emory - EP

Pharmaceutical compositions with antibiotic-immunostimulating activity

Pharmaceutical compositions containing erythromycin, or an ester thereof, and inosine, or an acidic derivative thereof, in molar ratios varying from 5:1 to 1:5, particularly in the form of a salt of erythromycin dipropionate (or of eryth...

A Fulvio，V Renzo，P Franco - EP