General asymmetric Strecker reaction catalyzed by urea derivatives.

A novel catalyst for the asymmetric cyanation of imines, the Strecker reaction, is discovered using combinatorial methods. The optimized structure consists...

P Vachal - Harvard University.

General nonmetal catalyst for the asymmetric Strecker reaction: Mechanism.

A novel catalyst for the asymmetric cyanation of imines, the Strecker reaction, is discovered using combinatorial methods. The optimized structure consists...

P Vachal，MS Sigman，T Kuribayashi，...

Structure-Based Analysis and Optimization of a Highly Enantioselective Catalyst for the Strecker Reaction

A mechanistic investigation of the asymmetric Strecker reaction catalyzed by a metal-free Schiff base catalyst was conducted. The active site of the cataly...

P Vachal，EN Jacobsen - 《Cheminform》

Recognition and activation by ureas and thioureas: stereoselective reactions using ureas and thioureas as hydrogen-bonding donors.

Recently, it has been shown that a hydrogen-bonding donor can be used as a general acid catalyst for various types of reactions in organic chemistry. ...

Y Takemoto - 《Organic & Biomolecular Chemistry》

General and practical catalytic enantioselective Strecker reaction of ketoimines: significant improvement through catalyst tuning by protic additives

Significant improvement in enantioselectivity and catalyst activity was achieved for the catalytic enantioselective Strecker reaction. Using a catalyst (1...

N Kato，M Suzuki，M Kanai，... - 《Tetrahedron Letters》

Br酶nsted acid-catalyzed efficient Strecker reaction of ketones, amines and trimethylsilyl cyanide

A general method for the one-pot, three-component Strecker reaction of ketones was developed using Br酶nsted acids as organocatalysts. A series of 伪-amino...

GW Zhang，DH Zheng，J Nie，... - 《Cheminform》

Recent Developments on Catalytic Applications of Nano-Crystalline Magnesium Oxide

Nanocrystalline metal oxides, MgO, CuO, ZnO, TiO 2 as catalysts or catalyst supports have been received much attention in the recent years, especially nan...

VR Chintareddy，ML Kantam - 《Catalysis Surveys from Asia》

A truly green synthesis of α-aminonitriles via Strecker reaction

The classical Strecker reaction is one of the simplest and most economical methods for the synthesis of racemic α-aminonitriles (precursor of α-amino acids) and pharmacologically useful compounds. Indium powder in water is shown to act...

D Bandyopadhyay，JM Velazquez，BK Banik - 《Organic & Medicinal Chemistry Letters》

Process for the preparation of N-alkanoyl-polyhydroxyalkylamines

The preparation von N-alkanoyl-polyhydroxyalkylamines I in which ##STR1## in which Z stands for the polyhydroxyalkyl radical of a monosaccharide or oligosaccharide,R.sup.1 denotes hydrogen or C.sub.1 -C.sub.8 alkyl andR.sup.2 denotes C. ...

B Strecker，H Wolf，G Wolf，... - US