Discovery of Bifunctional Thiourea/Secondary-Amine Organocatalysts for the Highly Stereoselective Nitro-Mannich Reaction of α-Substituted Nitroacetates
阅读量：
50
摘要：
NH group makes all the difference: The highly stereoselective nitro-Mannich reaction of -substituted nitroacetates and N-Boc aldimines was investigated catalyzed by novel chiral bifunctional thiourea/secondary-amine systems (an example is shown here). The presence of a basic NH group is crucial for the stereocontrol. The products with adjacent quaternary and tertiary chiral centers were directed isolated in moderate to good yields for an array of substrates
展开
DOI：
10.1002/chem.200801170
被引量：
年份：
2008
通过文献互助平台发起求助，成功后即可免费获取论文全文。
请先登入
相似文献
参考文献
引证文献
辅助模式
0
引用
文献可以批量引用啦~
欢迎点我试用！
