Antihypercholesterolemic compounds
6(R)- 2-(8'-acyloxy-2'-methyl-6'-methyl (or hydrogen)- polyhydronaphthyl-1')-ethyl!-4(R)-hydroxy-3,4,5,6-tetrahydro-2H-p yran-2- ones are prepared by acylation of the corresponding 8'-hydroxy compounds. The products are strong inhibitor...
WF Hoffman，RL Smith，AK Willard - US
Physiologically active substances and fermentative process for producing the same
6(R)- 2-(8'-acyloxy-2'-methyl-6'-methyl (or hydrogen)- polyhydronaphthyl-1')-ethyl!-4(R)-hydroxy-3,4,5,6-tetrahydro-2H-p yran-2- ones are prepared by acylation of the corresponding 8'-hydroxy compounds. The products are strong inhibitor...
A Endo，M Kuroda，A Terahara，...
ML-236B Derivatives and their preparation
6(R)- 2-(8'-acyloxy-2'-methyl-6'-methyl (or hydrogen)- polyhydronaphthyl-1')-ethyl!-4(R)-hydroxy-3,4,5,6-tetrahydro-2H-p yran-2- ones are prepared by acylation of the corresponding 8'-hydroxy compounds. The products are strong inhibitor...
Hypocholesteremic fermentation products
Substances isolated after cultivation of a microorganism belonging to the genus Aspergillus in a culture medium comprise compounds which have structures: ##STR1## Together with salts and esters of the carboxylic acid, these compounds for...
G Albers-Schonberg，RL Monaghan，AW Alberts，... - US
ML-236B Derivatives and their preparation
Compounds of formula (I): ##STR1## (wherein R represents a group of formula ##STR2## and the corresponding ring-closed lactones, salts (especially alkali metal salts) and esters (especially C.sub.1 -C. sub.5 alkyl esters) thereof may be ...
A Terahara，M Tanaka - US
Antihypercholesterolemic compounds
Compounds of formula (I): ##STR1## (wherein R represents a group of formula ##STR2## and the corresponding ring-closed lactones, salts (especially alkali metal salts) and esters (especially C.sub.1 -C. sub.5 alkyl esters) thereof may be ...
- US
Hypocholesterolemic fermentation products and process of preparation
Substances isolated after cultivation of a microorganism belonging to the genus Aspergillus in a culture medium include a compound with structural formula: ##STR1## Together with the corresponding free acid of the above ester, its salts ...
TYK Lam - US
ML-236B Derivatives and their preparation
Compounds of formula (I): ##STR1## (wherein R represents a group of formula ##STR2## and the corresponding ring-closed lactones, salts (especially alkali metal salts) and esters (especially C.sub.1 -C. sub.5 alkyl esters) thereof may be ...
A Terahara，M Tanaka
Hypocholesteremic fermentation products and process of preparation
Substances isolated after cultivation of a microorganism belonging to the genus Aspergillus in a culture medium comprise compounds which have structures: ##STR1## Together with salts and esters of the carboxylic acid, these compounds for...
G Albers-Schonberg，H Joshua，MB Lopez - US
Physiologically active substances
Physiologically active substances ML-236 of the formula ##SPC1## Wherein R is hydrogen atom, hydroxy group or 2-methylbutyryloxy group having cholesterol- and lipid-lowering effects in blood and liver and thus utility as hypocholesteremi...
A Endo，M Kuroda，A Terahara，... - US
