Catecholamine surrogates useful as β3 agonists

Compounds of the formula ##STR1## and pharmaceutically acceptable salts thereof. These compounds are beta three adrenergic receptor agonists and are useful, therefore for example, in the treatment of diabetes, obesity and gastrointestina...

PTW Cheng，GS Bisacchi，AV Gavai，... - CA

Sulfonic, phosphonic or phosphiniic acid β3 agonist derivatives

Compounds of the formula ##STR1## and pharmaceutically acceptable salts thereof wherein: A is a bond or --OCH--, where the oxygen is linked to R;

Sher, Philip M，A Mathur - US

Sulfonic, phosphonic or phosphiniic acid β.sub.3 agonist derivatives

Compounds of the formula ##STR1## and pharmaceutically acceptable salts thereof wherein: A is a bond or --OCH--, where the oxygen is linked to R;

Substituted basic 2-aminotetralin in pharmaceuticals

and their salts.

R Schohe，T Glaser，J Traber，...

Treating diabetes, obesity, achalasia, gastorintestinal disorders

R 4 is --SO 3 H, --P(O 2 H)R 5 , --P(O 2 R 5' )R 5 , --PO 3 H 2 , --PO 3 HR 5' or --PO 3 (R 5' ) 2 where R 5 and R 5' are independently lower al...

PM Sher，A Mathur - US

Process for the O-alkylation of N-(hydroxy) aralkylphenylethanolamines

A process for the preparation of a compound of formula ##STR1## wherein X represents hydrogen, halogen, trifluoromethyl or lower alkyl group; W represents methyl, Q represents hydrogen or W and Q, together, form an ethylene group and R' ...

R Boigegrain，R Cecchi，S Boveri - US

Substituted basic 2-aminotetralin useful as cardiotonic agents

For treatment of disorders of the central nervous system, the cardiovascular system or the intestinal tract, the new substituted basic 2-aminotetralins of the formula ##STR1## in which Rrepresents hydrogen or alkyl

R Schohe，T Glaser，J Traber，... - US

Substituted basic 2-aminotetralin in pharmaceuticals

and their salts.

GS Allen，T Glaser，R Schohe，... - US

Naphthyloxyacetic acid derivatives and drugs comprising the same as active ingredients

The naphthyloxyacetic acid derivatives of the formula (I) ##STR1## wherein A is H, --(alkylene)COOR, --(alkylene)CONRR, --(alkylene)OH, --(alkylene)tetrazole, --(alkylene)CN; E is single bond or alkylene; G is --S--, --SO--, --SO--, --O-...

Y Nagao，K Torisu，N Hamanaka - EP

Using substituted 5-(2-((2-aryl-2-hydroxyethyl)amino)propyl)-1,3-benzodioxole

Substituted 5-2-((2-aryl-2-hydroxyethyl)amino)propyl)-1,3-benzodioxoles having the structural formula: ##STR1## wherein R4, R5, R6, R7, and R8 are as herei...

RK Brazzell，B Dubnick - US