Métaphores, nomenclature et nouveaux paradigmes de signalisation par les récepteurs couplés aux protéines G

来自 EBSCO

阅读量:

36

作者:

Bouvier, Michel

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摘要:

1. Maehle AH, Prull CR, Halliwell RF. The emergence of the drug receptor theory. Nat Rev Drug Discov 2002 ; 1 : 637-41.2. Hill SJ. G-protein-coupled receptors: past, present and future. Br J Pharmacol 2006 ; 147 : S27-37.3. Lewontin R. La triple helice. Paris : Seuil, 2003 : 154 p.4. Chidiac P, Hebert T, Dennis M, Bouvier M. Inverse agonist activity of 2-adrenergic antagonists. Mol Pharmacol 1994 ; 45 : 490-9.5. Bond RA, Bouvier M. Inverse agonists and G protein-coupled receptors. In : Leff P, ed. Receptor-based drug design, chap. 16. New York : Marcel Dekker Inc., 1998 : 363-77.6. Azzi M, Charest P, Angers S, et al. -arrestin-dependent activation of MAPK pathway by 2-adrenergic receptor inverse agonists. Proc Natl Acad Sci USA 2003 ; 100 : 11406-11.7. Kenakin TP. Collateral efficacy in drug discovery: taking advantage of the good (allosteric) nature of 7TM receptors. Trends Pharmacol Sci 2007 ; 28 : 407-15.8. Galandrin S, Oligny-Longpre G, Bouvier M. The evasive nature of drug efficacy : implications for drug discovery. Trends Pharmacol Sci 2007 ; 28 : 423-30.9. Angers S, Salahpour A, Bouvier M. Dimerization: an emerging concept for G protein- coupled receptors, ontogeny and function. Annu Rev Pharmacol Toxicol 2002 ; 42 : 409-35.10. Smith NJ, Milligan G. Allostery at G protein-coupled receptor homo- and heteromers: uncharted pharmacological landscapes. Pharmacol Rev 2010 ; 62 : 701-25.11. Palczewski K, Kumasaka T, Hori T, et al. Crystal structure of rhodopsin: a G protein- coupled receptor. Science 2000 ; 289 : 739-45.12. Cherezov V, Rosenbaum DM, Hanson MA, et al. High-resolution crystal structure of an engineered human beta2-adrenergic G protein-coupled receptor. Science 2007 ; 318 : 1258-65.13. Rasmussen SG, Choi HJ, Rosenbaum DM, et al. Crystal structure of the human beta2 adrenergic G-protein-coupled receptor. Nature 2007 ; 450 : 383-7.14. Rosenbaum DM, Cherezov V, Hanson MA, et al. GPCR engineering yields high- resolution structural insights into beta2-adrenergic receptor function. Science 2007 ; 318 : 1266-73.

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DOI:

10.1051/medsci/20122810002

被引量:

1

年份:

2012

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