Ontogeny of the v-erbA oncoprotein from the thyroid hormone receptor: an alteration in the DNA binding domain plays a role crucial for v-erbA function.

The avian erythroblastosis virus v-erbA oncogene is imprecisely derived from a cellular gene (c-erbA) encoding a thyroid hormone receptor: the v-erbA prote...

BG Bonde，M Sharif，ML Privalsky - 《Journal of Virology》

Cross-inhibition of angiotensin AT1 receptors supports the concept of receptor oligomerization

The functional relevance of G protein-coupled receptor dimerization or oligomerization has been raised in a number of different processes, including ontogeny, ...

E Karip，G Turu，K Süpeki，... - 《Neurochemistry International》

Métaphores, nomenclature et nouveaux paradigmes de signalisation par les récepteurs couplés aux protéines G

Dimerization: an emerging concept for G protein- coupled receptors, ontogeny and function. Annu Rev Pharmacol Toxicol 2002 ; 42 : 409-35.10. Smith NJ, Milligan G. Allostery at G protein-coupled receptor homo- and heteromers: uncharted...

M Bouvier - 《Médecine/sciences》

TEF, a transcription factor expressed specifically in the anterior pituitary during embryogenesis, defines a new class of leucine zipper proteins

We have identified and characterized a new member of the leucine zipper (bZIP) gene family of transcription factors, thyrotroph embryonic factor (TEF). Ana...

DW Drolet，KM Scully，DM Simmons，... - 《Genes & Development》

Induction of Human Fetal Globin Gene Expression by a Novel Erythroid Factor, NF-E4

The stage selector protein (SSP) is a heteromeric complex involved in preferential expression of the human gamma-globin genes in fetal-erythroid cells. We ...

W Zhou，DR Clouston，X Wang，... - 《Molecular & Cellular Biology》

Graphical computations of the occultation of star clusters

In the interferon-gamma (IFNgamma)-activated Janus Kinase (JAK)/signal transducer and activator of transcription 1 (STAT1) pathway, multiple steps of STAT1...

E Sperra - 《Popular Astronomy》

Abstract 3850: FOXP3 dimerization by stapled alpha-helical peptides alters regulatory T cell function

Regulatory T cells (Tregs) are critical for the maintenance of immune tolerance and control of immune responses to foreign agents. Tregs depend upon the transcriptional protein FOXP3 for their ontogeny and genetic orchestration of their ...

R Eclov，M Fefferman，R Samaeekia，... - 《Cancer Research》

Signaling FcR gamma and TCR subunit homologs in the amphibian Xenopus laevis

The genes encoding FcRgamma and TCRzeta homologs were identified using a bioinformatic approach in the amphibian Xenopus laevis. Deduced amino acid sequenc...

Guselnikov SV.Bell A.Najakshin AM.Robert J.Taranin AV. - Developmental and Comparative Immunology: Ontogeny, Phylogeny, Aging: The Official Journal of the International Society of Developmental and Comparative Immunology