Nature of the antigenic complex recognized by T lymphocytes: specific sensitization by antigens associated with allogeneic macrophages.

Alloreactive guinea pig thymus-derived (T) cells generated in vitro were rendered unresponsive to allogeneic macrophages by treatment with bromodeoxyuridin...

DW Thomas，EM Shevach - 《Proceedings of the National Academy of Sciences of the United States of America》

Nature of the antigenic complex recognized by T lymphocytes. I. Analysis with an in vitro primary response to soluble protein antigens.

In order to analyze the genetic factors involved in the regulation of macrophage-T-cells interaction we have developed an in vitro primary response to solu...

Thomas，D. W. - 《Journal of Experimental Medicine》

Melanoproteins. I. Reactions between enzyme-generated quinones and amino acids.

1. 1. A systematic survey of the reactions of compounds containing the functional groups of proteins with melanogenic systems comprised of o-diphenol oxidase and catechol, 4-methylcatechol, 3,4-dihydroxyphenylalanine, or 5,6-dihydroxyind...

HS Mason，EW Peterson - 《Biochimica Et Biophysica Acta》

Structure and Absorption Spectra. II. 3-Acetoxy-Δ5-(6)-nor-cholestene-7-carboxylic Acid

1. 1. A systematic survey of the reactions of compounds containing the functional groups of proteins with melanogenic systems comprised of o-diphenol oxidase and catechol, 4-methylcatechol, 3,4-dihydroxyphenylalanine, or 5,6-dihydroxyind...

R. B. Woodward，A. F. Clifford - 《J. Am. Chem:soc》

ChemInform Abstract: MOLECULAR ORBITAL STUDY ON THE REACTION MECHANISM OF IRREVERSIBLE ENZYME INHIBITORS

1. 1. A systematic survey of the reactions of compounds containing the functional groups of proteins with melanogenic systems comprised of o-diphenol oxidase and catechol, 4-methylcatechol, 3,4-dihydroxyphenylalanine, or 5,6-dihydroxyind...

C Nagata，T Yamaguchi - 《Chemischer Informationsdienst》

Molecular orbital study on the reaction mechanism of irreversible enzyme inhibitors

By means of the molecular orbital method, the reaction mechanism of the specific and irreversible enzyme inhibitors, such as cycloserine, L-2-amino-4-metho...

Chikayoshi，Nagata，Tamie，... - 《Journal of Medicinal Chemistry》

Selective labeling of human erythrocyte membrane components with tritiated trinitrobenzenesulfonic acid and picryl chloride

Treatment of intact human erythrocytes with tritiated trinitrobenzenesulfonic acid (TNBS) and picryl chloride (PC) resulted in labeling of their membrane components. Separation of these components by polyacrylamide gel electrophoresis in...

JJ Arrotti，JE Garvin - 《Biochemical & Biophysical Research Communications》

AN IMPROVED SYNTHESIS OF 3-N-PENTADECYL CATECHOL (3-PDC)

4-Alkoxymethyl-2-bromo-2-ethoxycarbonylbutanolides were obtained with good yields by the bromination of 4-alkoxymethyl-2-ethoxycarbonylbutanolides with bro...

CR Dawson，GP Ng - 《Organic Preparations & Procedures International》

Nature of the antigenic complex recognized by T lymphocytes. VII. Evidence for an association between TNP-conjugated macrophage membrane components and Ia antigens

In the present study we examined the effects of anti-sera directed against guinea pig Ia antigens on the ability of TNP-conjugated macrophages to stimulate TNP-specific T lymphocyte proliferation. Treatment of macrophages with anti-Ia se...

DW Thomas，EM Shevach - 《Journal of Immunology》

Nature of the antigenic complex recognized by T lymphocytes. VI. The effect of anti-TNP antibody on T cell responses to TNP-conjugated macrophages.

In the present study we examined the effects of anti-sera directed against guinea pig Ia antigens on the ability of TNP-conjugated macrophages to stimulate TNP-specific T lymphocyte proliferation. Treatment of macrophages with anti-Ia se...

DW Thomas，EM Shevach - 《Journal of Immunology》