Substituted acyl derivatives of 1,2,3,4-tetrahydroisoquinoline-3- carboxylic acids
申请(专利)号:
ZA19810006332
申请日期:
1981-09-11
公开/公告号:
ZA816332B
公开/公告日期:
1982-09-29
申请(专利权)人:
WARNER LAMBERT CO
被引量:
摘要:
Substituted acyl derivatives of 1,2,3,4-tetrahydroisoquinoline- 3- carboxylic acids and the pharmaceutically acceptable salts thereof are produced by coupling a suitably substituted 1,2,3,4- tetrahydroisoquinoline with a suitably substituted amino acid and when desired hydrolyzing or removing protecting groups of the resulting product. The compounds of the invention, their salts and pharmaceutical compositions thereof are useful as antihypertensive agents.
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